Direct Measurement of the Thermodynamic Parameters of Amyloid Formation by Isothermal Titration Calorimetry
نویسندگان
چکیده
منابع مشابه
Direct measurement of the thermodynamic parameters of amyloid formation by isothermal titration calorimetry.
Amyloid fibril deposition is associated with over 20 degenerative diseases, including Alzheimer's, Parkinson's, and prion diseases. Although research over the last few years has revealed the morphology and structural features of the amyloid form, knowledge about the thermodynamics of amyloid formation is limited. Here, we report for the first time a direct thermodynamic study of amyloid formati...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m409677200